Relief from IL-1

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Relief from IL-1

On page 1407, Decker and colleagues trick HIV into exposing itself. This trick revealed that a majority of infected individuals have broadly cross-reactive neutralizing antibodies against HIV in their circulation. Antibodies that neutralize diverse strains of HIV have been difficult to find, despite decades of searching. Several gp120-specific neutralizing anti-bodies have been cloned. Some of ...

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بررسی غلظت IL-1? و IL-6 و IL-8 و TNF-? در کنسانتره های پلاکتی

Background: As increase of cytokines (like IL-1 , IL-6 , IL-8 and TNF- ) in platelet concentrates (PCs) during storage are involved in Febrile Non Hemolytic Transfusion Reactions (FNHTRs) after Platelet transfusion, the aim of this study was the survey of these cytokines level in PCs produced in Tehran Blood Center. Materials and Methods: This study proposed to determine if WBC reduction in P...

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Relief from Contact Inhibition

The viral transformation of normal into tumorigenic cells is a system under active investigation . The fact that transformation is accompanied by loss of contact-inhibition has focused attention on other situations in which confluent cells can be caused to resume movement and cell division . One such system is the serum-stimulated relief of contact-inhibition in cultured fibroblasts (1, 2, 3) ....

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Transition from interleukin 1 beta (IL-1 beta) to IL-1 alpha production during maturation of inflammatory macrophages in vivo

In situ production of interleukin 1 alpha (IL-1 alpha) and IL-1 beta was investigated in Peyer's patches (PP) of mice undergoing an acute bacterial infection with Yersinia enterocolitica O8. Synthesis of IL-1 beta, as determined by immunohistochemistry, was found primarily in monocytes migrating into the inflamed PP. In comparison, synthesis of IL-1 alpha was temporarily delayed by at least 24 ...

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Expression of IGF-1, IL-27 and IL-35 Receptors in Adjuvant Induced Rheumatoid Arthritis Model

Background: IGF-1 and certain other cytokines have been shown to exert inflammatory/anti-inflammatory roles in chronic joint diseases. Objective: To assess the effect of IGF-1, IL-27 and IL-35, their interaction and their receptor expression in a rheumatoid arthritis model. Methods: Freund’s adjuvant-induced chronic joint inflammation was operated on 160 male rats. Animals were divided into his...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 2005

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem2019iti2